|学科||生物医学工程 Biomedical Engineering|
|国家/州||United States of America|
Refining a Novel Device to Decrease the Risk of Vesicovaginal and Rectovaginal Fistulae during Labor
In developing areas where professional medical care is scarce, the labor complications that result in the development of obstetric fistulae are common and the effects devastating, with over two million women currently suffering from severe incontinence, shame, and terrible pain. The purpose of this experiment was to refine and redesign a cost-effective and portable device to decrease the risk of vesicovaginal and rectovaginal fistulae during childbirth. From the use of an improved precise, self-built CAD and FEA model of female pelvic anatomy from anonymized CT scan data and both a mechanical simulation and computational fluid dynamics simulation program, different designs and design materials were tested, yielding a final device design. Then, the stress-distributing properties as well as the amount of strain experienced of the final design was compared with that of using no device at all. For the revised prototype, the mean stress at the key point showed a percent difference of almost 200% for all three tests, and each t-test performed for each test yielded a p-value much less than the declared alpha value of 0.05, showing that the device significantly decreases the amount of stress at points where fistulae commonly occur. A more complex model with isolated contact pairs and mathematical modeling, simulation, and inclusion of fluid factors contributed to the improved accuracy of the results and design. However, this design and the model will be further optimized with daily redesigning and simulation.
英特尔国际科学与工程大奖赛，简称 "ISEF"，由美国 Society for Science and the Public（科学和公共服务协会）主办，英特尔公司冠名赞助，是全球规模最大、等级最高的中学生的科研科创赛事。ISEF 的竞赛学科包括了所有数学、自然科学、工程的全部领域和部分社会科学。ISEF 素有全球青少年科学竞赛的“世界杯”之美誉，旨在鼓励学生团队协作，开拓创新，长期专一深入地研究自己感兴趣的课题。
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Projects that involve the application of engineering principles and design concepts to medicine and biology for healthcare purposes including diagnosis, monitoring and therapy. Prominent biomedical engineering applications include the development of biocompatible prostheses, various diagnostic and therapeutic medical devices ranging from clinical equipment to micro-implants, common imaging equipment such as MRIs and EEGs, regenerative tissue growth, pharmaceutical drugs and therapeutic biologicals.
Biomaterials and Regenerative Medicine (BMR): These studies involve the creation or use of biomaterials or biocompatible materials to construct a whole or a part of a living structure. These studies can include scaffolds for recruiting or supporting regenerative cells or tissues or the engineering designs for creating the correct environment for regenerative growth.
Biomechanics (BIE): Studies that apply classical mechanics (statics, dynamics, fluids, solids, thermodynamics, and continuum mechanics) to understand the function of biological tissues, organs, and systems and solve biological or medical problems. It includes the study of motion, material deformation, flow within the body and in devices, and transport of chemical constituents across biological and synthetic media and membranes.
Biomedical Devices (BDV): The study and/or construction of an apparatus that use electronics and other measurement techniques to diagnose, prevent and/or treat diseases or other conditions within or on the body.
Biomedical Imaging (IMG): The study and/or construction of an apparatus or technique that combines knowledge of a unique physical phenomenon (sound, radiation, magnetism, etc) with high speed electronic data processing, analysis and display to generate an image to support biomedical advances and procedures.
Cell and Tissue Engineering (CTE): Studies that utilize the anatomy, biochemistry and mechanics of cellular and sub-cellular structures in order to understand disease processes and to be able to intervene at very specific sites.
Synthetic Biology (SYN): Studies that involve the design and construction of new biological parts, devices and systems. Such studies include biological circuit design, genetic circuits, protein engineering, nucleic acid engineering, rational design, directed evolution and metabolic engineering.
OTH Other (OTH): Studies that cannot be assigned to one of the above subcategories. If the project involves multiple subcategories, the principal subcategory should be chosen instead of Other.